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Poster B12 in Poster Session B - Thursday, August 8, 2024, 1:30 – 3:30 pm, Johnson Ice Rink
Interictal epileptiform discharges disrupt neural computations underlying cognitive control and value-based decision making
Niloufar Shahdoust1 (), Rhiannon Cowan1, Alexander Price1, Bornali Kundu1, Tyler Davis1, John Rolston2, Shervin Rahimpour1, Elliot Smith1; 1University of Utah, 2Harvard Medical School
This research investigates how Interictal Epileptiform Discharges (IEDs) affect cognitive control and decision-making in epileptic patients. Using the Balloon Analog Risk Task (BART) to examine decisions made under risk, our study suggests that IEDs lengthen both response times and balloon inflation times and indicates that these discharges disrupt cognitive functions associated with the prefrontal cortex. The results emphasize the need for customized interventions to mitigate these effects and improve cognitive efficiency and decision-making quality in individuals with epilepsy.
Keywords: Interictal epileptiform discharge Human prefrontal cortex Decision making Cognitive control